The Determination of Antioxidant Activity of Ethanol Extracts of Gynostemma Pentaphyllum

Document Type : Research Paper

Authors

1 Department of Pharmacognosy with a Course in Botany and The Basics of Herbal Medicine, Faculty of Pharmacy, Bashkir State Medical University, Ufa, Russian Federation

2 Central Research Laboratory, Bashkir State Medical University, Ufa, Russian Federation.

3 Department of Analytical, Physical and Colloidal Chemistry; Department of Pharmaceutical Science; Institute of Pharmacy, Moscow, Russian Federation

4 Department of Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran

5 Department of Pharmacognosy with a Course in Botany and The Basics of Herbal Medicine, Faculty of Pharmacy, Bashkir State Medical University, Ufa, Russian Federation.

10.22034/ijps.2021.522481.1779

Abstract

Inflammatory reactions of active radicals play a primary role in many vital circumstances, and if they are not neutralized and persist in the body, many diseases will occur. Antioxidants are the very critical resources available in the body to eliminate these free radicals. Medicinal herbs have been used extensively in the treatment of diseases for centuries. Gynostemma Pentaphyllum is grown in many different locations of Europe and Asia is an adaptogenic plant that is rich in antioxidants. During this study, the antioxidant effects of Gynostemma Pentaphyllum extract are evaluated using two different methods of adrenaline autooxidation and Chemiluminescence, both patented in Russia. Our results show that the organic solvent is more suitable for the extraction of these antioxidants with the ratio of 70% ethanolic extract being yield in more extraction. This preliminary work might open a new door for future studies on the antioxidant effects of this herb grown in Russia for the treatment of inflammations and other diseases with such pathology.

Keywords